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KMID : 1144320140460030209
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감염과 화학요법
2014 Volume.46 No. 3 p.209 ~ p.215
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Aspergillus Tracheobronchitis and Influenza A Co-infection in a Patient with AIDS and Neutropenia
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Lee Ji-Yong
Joo Eun-Jeong
Yeom Joon-Sup
Song Jae-Uk
Yim Seo-Hyung
Shin Dong-Suk
Yu Jung-Hee
Ju Deok-Yun
Yim Jae-Wan
Song Young-Seok
Sohn Yoon-Jeong
Do Sung-Im
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Abstract
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Aspergillus tracheobronchitis (AT), an unusual form of invasive pulmonary aspergillosis (IPA), is characterized by pseudomembrane formation, ulcer or obstruction that is predominantly confined to tracheobronchial tree. Hematologic malignancies, neutropenia, solid organ transplantation, chronic corticosteroid therapy and acquired immunodeficiency syndrome (AIDS) are known to be major predisposing conditions. However, since the introduction of highly active antiretroviral therapy, there is only one reported case of AT in AIDS patient. After pandemic of influenza A/H1N1 2009, there are several reports of IPA in patient with influenza and most of them received corticosteroid or immunosuppressive therapy before the development of IPA. We present a 45 year-old AIDS patient with influenza A infection who developed pseudomembranous AT without corticosteroid use or immunosuppressive therapy.
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KEYWORD
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Aspergillus, Bronchitis, Influenza, AIDS
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